Podophyllum hexandrum is succulent erect herb, glabrous, up to 30 cm tall with creeping long knotty rhizomes. Stem one or two, simple, leafy without a top. Leaves alternate, palmate, deeply divided in 3-5 lobes, toothed, purple spotted.
Flowers are white to pinkish in color, Sepals are 3 in number and petaloid. Stamens are usually 6. Fruits are ovoid, pulpy 5 cm long and scarlet when ripe.
Rhizomes are used for typhoid fever, jaundice, dysentery, chronic hepatitis, scrofula, rheumatism, skin diseases, tumerous growth, kidney & bladder problems. The plant is also used for gonorrhea and syphilis. The podophyllum is used as a purgative and also for treatment of vaginal warts.